Actively Recruiting
Efficacy of Quantum Molecular Resonance in Neuropathic Corneal Pain and Corneal Nerve Regeneration
Led by Singapore Eye Research Institute · Updated on 2025-09-19
30
Participants Needed
1
Research Sites
165 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to evaluate whether Quantum Molecular Resonance (QMR) treatment can effectively reduce eye pain and stimulate corneal nerve regeneration in patients with neuropathic corneal pain (NCP). Participants diagnosed with NCP will attend a total of nine study visits, consisting of one baseline assessment and eight QMR treatment sessions. At each visit, participants will undergo a series of clinical examinations to evaluate changes in the ocular surface, corneal nerves, and tear proteins, and will complete questionnaires regarding their symptoms, eye pain, and quality of life. The investigators will compare these outcomes before and after QMR treatment to determine whether QMR treatment alleviates NCP symptoms and enhances ocular surface and corneal nerve health. The investigators hypothesize that QMR treatment will provide notable pain relief, promote corneal nerve regeneration, and improve overall quality of life for NCP patients.
CONDITIONS
Official Title
Efficacy of Quantum Molecular Resonance in Neuropathic Corneal Pain and Corneal Nerve Regeneration
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be at least 21 years of age.
- Male or Female gender.
- Any race (Chinese, Malay, Indian, Eurasian, Others).
- Diagnosed with neuropathic corneal pain showing symptoms like burning, stinging, photophobia, pain, or severe dryness, with minimal slit-lamp findings and corneal nerve abnormalities seen on IVCM.
- Willing to undergo all eye examinations required by the study.
You will not qualify if you...
- Pregnant women.
- Participants with active implantable devices such as pacemakers or hearing aids.
- Patients undergoing cancer treatment or who had eye surgery within the last month.
- Those with ocular infection in the past 6 months, active ocular infection or inflammation, or other eye diseases that could cause eye pain such as uveitis.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Singapore National Eye Centre
Singapore, Singapore, S169856
Actively Recruiting
Research Team
Y
Yu-Chi Liu, MD, MCI, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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