Actively Recruiting
The Efficacy of Remimazolam on Incidence of Hypoxia During Sedated Transvaginal Oocyte Retrieval: A Multicenter Randomized Controlled Trial.
Led by Diansan Su · Updated on 2026-01-13
400
Participants Needed
3
Research Sites
62 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hypoxia is the most common adverse reaction during sedation outside the operating room.Exploring novel drug combinations to reduce the incidence of hypoxia during sedation in patients undergoing transvaginal oocyte retrieval procedures enhances patient safety and lowers perioperative adverse event rates. This multicenter, prospective, randomized, controlled clinical study will compare the hypoxia incidence rate of the remimazolam-alfentanil combination against the commonly used propofol-alfentanil combination.
CONDITIONS
Official Title
The Efficacy of Remimazolam on Incidence of Hypoxia During Sedated Transvaginal Oocyte Retrieval: A Multicenter Randomized Controlled Trial.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Females aged 18 to 50 years planning to undergo painless oocyte retrieval
- Classified as American Society of Anesthesiologists (ASA) physical status I-II
You will not qualify if you...
- Contraindications to general anesthesia
- History of acute or severe cardiovascular disease
- Acute upper respiratory infection
- Chronic obstructive pulmonary disease (COPD) or asthma attacks
- Uncontrolled hypertension
- Alcohol abuse
- Severe liver or kidney failure
- Severe cardiovascular disease or psychiatric disorders
- Hearing impairment preventing communication
- History of long-term sedative or opioid use
- Allergies to benzodiazepines, flumazenil, opioids and their antidotes, propofol, eggs, or soy products
- Oxygen saturation (SpO2) below 95% while breathing room air after entering the room
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Dongyang People's Hospital
Dongyang, Zhejiang, China, 322100
Not Yet Recruiting
2
The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
3
Lishui People's Hospital
Lishui, Zhejiang, China, 323000
Not Yet Recruiting
Research Team
D
Diansan Su, Dr.
CONTACT
S
Shuhan Gu, MD.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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