Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06462417

Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis

Led by Zheng Liu · Updated on 2025-05-07

15

Participants Needed

2

Research Sites

50 weeks

Total Duration

On this page

Sponsors

Z

Zheng Liu

Lead Sponsor

N

National Natural Science Foundation of China

Collaborating Sponsor

AI-Summary

What this Trial Is About

The most important treatment for AR is topical nasal medications (including nasal corticosteroids, nasal antihistamines, nasal decongestants, and nasal saline irrigation etc.), which are still limited. Arbidol may inhibit molecular targets involved in the pathogenesis of AR. This study intends to explore the effect of Arbidol in the treatment of allergic rhinitis and evaluate its efficacy and safety.

CONDITIONS

Official Title

Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with allergic rhinitis according to official Chinese guidelines
  • At least two nasal symptoms are moderate or worse, including sneezing, runny nose, nasal itching, or congestion
  • Female participants are not pregnant or breastfeeding and have no plans for pregnancy or breastfeeding during the treatment
  • No participation in other clinical trials within the past three months and agreement to avoid other trials during this study
  • Understanding of the study purpose and procedures and voluntary agreement to participate with adherence to study requirements
Not Eligible

You will not qualify if you...

  • Allergy to Arbidol
  • Abnormal liver or kidney function above specified limits
  • Abnormal ECG results or clinically significant heart rhythm issues
  • Severe or acute asthma
  • Structural heart disease, severe hypertension, diabetes, hyperthyroidism, cancer, immune problems, or mental illness
  • Nasal conditions like polyps, severe septum deviation, sinusitis, or hypertrophic rhinitis
  • Participation in other clinical studies within 3 months
  • Pregnancy, breastfeeding, or positive pregnancy test or plans during the treatment
  • Drug or alcohol abuse
  • Allergen-specific immunotherapy within the past 3 years
  • Positive infectious disease tests (hepatitis B, hepatitis C, AIDS, syphilis)
  • Other reasons deemed unsuitable by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology

Wuhan, Hubei, China, 430000

Actively Recruiting

2

Department of ENT, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China, 430030

Actively Recruiting

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Research Team

Z

Zheng Liu, Doctor

CONTACT

M

Ming Zeng, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis | DecenTrialz