Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT04745221

Efficacy and Safety of Auto-FMT in Preventing aGVHD

Led by The First Affiliated Hospital of Soochow University · Updated on 2025-12-31

100

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluation the efficacy and safety of autologous fecal bacteria transplantation in preventing acute graft versus host disease after haploidentical hematopoietic stem cell transplantation. Bone marrow transplant patients were recruited.

CONDITIONS

Official Title

Efficacy and Safety of Auto-FMT in Preventing aGVHD

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients must be undergoing haploidentical hematopoietic stem cell transplantation (haplo-HSCT)
  • Bacteroidetes level greater than 0.1%
  • Inverse Simpson diversity index of 2 or higher
  • Age between 18 and 60 years
Not Eligible

You will not qualify if you...

  • Presence of gastrointestinal diseases
  • Age greater than 60 years or less than 10 years
  • Use of probiotics or prebiotics before enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ye Zhao

Suzhou, Jiangsu, China, 215006

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

2

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Efficacy and Safety of Auto-FMT in Preventing aGVHD | DecenTrialz