Safety and Effectiveness of a Ropivacaine, Sodium Bicarbonate, and Dexamethasone Cocktail for Local Pain Relief After Daytime Laparoscopic Gallbladder Surgery

What this Trial Is About

Researchers are studying if a mixture of ropivacaine, sodium bicarbonate, and dexamethasone used for local pain relief at the incision site is safe and effective in patients having outpatient laparoscopic gallbladder removal. The main question is whether this cocktail reduces moderate to severe pain during movement within six hours after surgery compared to using ropivacaine alone. Participants will receive either the cocktail or ropivacaine injected locally at the end of their surgery. The study groups include those receiving the combined cocktail and those receiving only ropivacaine. This is a randomized, triple-blind trial designed to compare the two treatments. Participants will be asked about their pain using a Numeric Rating Scale at rest and during movement at multiple times after surgery 2, 6, 12, 24 hours, and then at 3, 7, 30 days, and 3 months. Researchers will also monitor if opioid pain medication is needed after surgery. The study monitors participants over several months to assess pain levels and treatment effects.

Efficacy and Safety of Cocktail of Ropivacaine for Local Infiltration Analgesia in Patients Undergoing Laparoscopic Cholecystectomy