Actively Recruiting
Efficacy and Safety of Cocktail of Ropivacaine for Local Infiltration Analgesia in Patients Undergoing Laparoscopic Cholecystectomy
Led by Sichuan Provincial People's Hospital · Updated on 2025-02-19
210
Participants Needed
1
Research Sites
28 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if the use of cocktail of ropivacaine,sodium bicarbonate and dexamethasone for incision local infiltration analgesia in patients undergoing ambulatory laparoscopic cholecystectomy is safe and effective. The main questions it aims to answer are: Does the cocktail lower the The incidence of moderate to severe pain during movement stages within six hours after surgery. Researchers will compare the cocktail to ropivacaine for incision local infiltration analgesia to see if the cocktail works to moderate the postoperative pain of ambulatory laparoscopic cholecystectomy patients. Participants will: Receive the cocktail or ropivacaine for incision local infiltration analgesia at the end of the surgery. Answer the questions about postsurgical pain at rest or during motion(using a Numeric Rating Scale (NRS) of 0 to 10. Pain measurements were performed at 2, 6, 12, 24 hours,3,7,30 days and 3 months postoperatively.
CONDITIONS
Official Title
Efficacy and Safety of Cocktail of Ropivacaine for Local Infiltration Analgesia in Patients Undergoing Laparoscopic Cholecystectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing daytime laparoscopic cholecystectomy at Sichuan Provincial People's Hospital
- Age between 18 and 70 years
- American Society of Anesthesiologists physical status classification I or II
- Body mass index (BMI) between 18 and 30 kg/m²
- No communication barriers and able to understand the study and pain scale
- Signed informed consent form
You will not qualify if you...
- Allergy to any drugs used in this study
- History of chronic pain or long-term use of analgesics equivalent to 10 mg or more oxycodone per day
- Alcohol abuse
- Gastrointestinal bleeding or perforation after using nonsteroidal anti-inflammatory drugs
- Ischemic heart disease, peripheral arterial or cerebrovascular disease
- Pulmonary heart disease
- Active peptic ulcer or gastrointestinal bleeding
- Inflammatory bowel disease
- Use of monoamine oxidase inhibitors or discontinuation within 2 weeks
- Preoperative pain score (NRS) of 4 or higher
- Participation in other clinical studies within the last 3 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sichuan Provincial People's Hospital
Chengdu, Sichuan, China, 610000
Actively Recruiting
Research Team
Y
Yue Liu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here