Actively Recruiting
Efficacy and Safety of Colorectal Anastomotic Leak Testing
Led by Nanchong Central Hospital · Updated on 2026-03-31
264
Participants Needed
1
Research Sites
223 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the effectiveness of the gastroscopy, air, and methylene blue (GAM) leak testing in reducing the incidence of postoperative anastomotic complications, especially anastomotic leakage, in patients with colorectal cancer. The primary outcomes included is the incidence of anastomotic complications (mainly anastomotic leak) within 30 days after surgery
CONDITIONS
Official Title
Efficacy and Safety of Colorectal Anastomotic Leak Testing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with colorectal cancer by pathology and scheduled for surgical treatment who meet the surgical indications.
- Aged between 18 and 85 years.
- American Society of Anesthesiologists (ASA) physical status classification is I - III.
- The patient or his/her legal representative can understand and sign the informed consent form and is willing to cooperate throughout the study process.
You will not qualify if you...
- Patients with preoperatively diagnosed anastomotic leak or other severe abdominal infections.
- Patients with severe cardiovascular and cerebrovascular diseases (such as recent myocardial infarction, unstable angina pectoris, severe heart failure, acute cerebral infarction, etc.) who cannot tolerate surgery and related tests.
- Patients with severely impaired liver and kidney function (liver function Child - Pugh classification C or above, creatinine clearance rate < 30 ml/min).
- Patients with coagulation disorders (such as platelet count < 50×10⁹/L, international normalized ratio (INR) > 1.5, etc.) that cannot be corrected or are receiving anticoagulant therapy that cannot be adjusted.
- Patients with a history of abdominal radiotherapy or multiple abdominal surgeries and severe abdominal adhesions that may affect the operation and detection procedures.
- Patients with other malignant tumors who are receiving active anti-tumor treatment such as radiotherapy and chemotherapy.
- Patients with mental illness or cognitive impairment who cannot cooperate with the study process and follow-up.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Nanchong Central Hospital
Nanchong, Sichuan, China
Actively Recruiting
Research Team
Y
Yunhong Tian, doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
8
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