Actively Recruiting
The Efficacy and Safety of HRS8179 in Severe Cerebral Edema Following Large Hemispheric Infarction
Led by Beijing Suncadia Pharmaceuticals Co., Ltd · Updated on 2025-08-22
725
Participants Needed
1
Research Sites
133 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study is being conducted to evaluate the efficacy, and safety of HRS8179 injection in preventing and treating severe cerebral edema after large area cerebral infarction in the cerebral hemisphere
CONDITIONS
Official Title
The Efficacy and Safety of HRS8179 in Severe Cerebral Edema Following Large Hemispheric Infarction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fully understand and voluntarily participate in this trial, and sign the informed consent form (participant or legal representative may sign)
- Clinical diagnosis of acute ischemic stroke in the middle cerebral artery territory
- National Institutes of Health Stroke Scale (NIHSS) score of 10 or higher at screening
- Large hemispheric infarction with lesion volume 80 to 160 cm3 on MRI diffusion-weighted imaging or CT perfusion
- Treatment started within 10 hours of stroke onset or last known normal time
You will not qualify if you...
- Likely to withdraw supportive treatment on the first day
- Evidence of a serious infarction in the opposite hemisphere affecting function
- Clinical signs of brain herniation
- CT/MRI shows a midline shift greater than 2 mm
- CT/MRI shows cerebral hemorrhage
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Tiantan Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100000
Actively Recruiting
Research Team
Y
Yu Gao
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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