Actively Recruiting

Phase Not Applicable
Age: 40Years - 85Years
All Genders
NCT07329361

Efficacy and Safety of Intra-articular Injections of Frozen Platelet-Rich Plasma in Patients With Knee Osteoarthritis

Led by MiKS Hospital · Updated on 2026-01-09

60

Participants Needed

1

Research Sites

106 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Evaluation of intra-articular injections in knee osteoarthritis using frozen-stored PRP. Compared with intra-articular injections of PRP applied at the time of collection.

CONDITIONS

Official Title

Efficacy and Safety of Intra-articular Injections of Frozen Platelet-Rich Plasma in Patients With Knee Osteoarthritis

Who Can Participate

Age: 40Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of both sexes
  • Aged between 40 and 85 years old
  • Diagnosed with osteoarthritis through clinical radiological examination
  • Joint pain equal to or less than 75 points on the KOOS (pain)
  • Radiological severity grades 1, 2, and 3 according to the Ahlbäck scale
  • Indication for intra-articular PRP infiltration
  • Body Mass Index values between 20 and 35
  • Negative serological tests for syphilis, HIV, HBV, and HCV
  • Possibility of observation during the follow-up period
  • Signature of informed consent
Not Eligible

You will not qualify if you...

  • Body mass index greater than 35
  • Diagnosed polyarticular disease
  • Previous arthroscopy in the last year
  • Severe mechanical deformity
  • Intra-articular hyaluronic acid injection in the last 12 months
  • Intra-articular corticosteroid or PRP injection in the last 6 months
  • Systemic autoimmune rheumatic disease (connective tissue diseases and systemic necrotizing vasculitis)
  • Anemia or other hematological disorders
  • Positive serological tests for syphilis, HIV, HBV, and HCV
  • Undergoing immunosuppressive treatments
  • Poorly controlled diabetes mellitus
  • Patients allergic to paracetamol
  • Pregnancy or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Arthroscopic Surgery Unit, MiKS Hosptial

Vitoria-Gasteiz, Araba/Álava, Spain, 01010

Actively Recruiting

Loading map...

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here