Actively Recruiting
Efficacy and Safety of Intrathecal Morphine for Postoperative Pain Management Following Planned Caesarean Section
Led by Anne Juul Wikkelsø · Updated on 2025-12-19
1312
Participants Needed
8
Research Sites
102 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if morphine added to the spinal anaesthesia can improve postoperative pain treatment for patients undergoing caesarean section, without increasing the risk of serious adverse events in mother and baby. The main questions it aims to answer are: * Is the treatment effective in preventing postoperative pain? * Is the treatment safe for both mother and baby? Participants will be given a normal spinal anaesthesia with addition of either morphine or sodium chloride (inactive substance). All participants will receive standard postoperative pain treatment, including morphine tablets as needed. Researchers will collect data from the electronic medical record and ask the participants to fill out questionnaires about pain levels and possible side effects.
CONDITIONS
Official Title
Efficacy and Safety of Intrathecal Morphine for Postoperative Pain Management Following Planned Caesarean Section
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years or older
- Singleton pregnancy
- Scheduled for planned caesarean section under spinal anaesthesia
- Provided written informed consent
You will not qualify if you...
- Allergy or contraindication to trial medications
- Planned postoperative epidural due to expected difficult pain management
- Planned combined spinal-epidural as primary anaesthesia
- Inability to understand and read Danish
- Previous participation in this trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
Aarhus University Hospital
Aarhus, Denmark, 8200
Actively Recruiting
2
Copenhagen University Hospital - Rigshospitalet
Copenhagen, Denmark, 2100
Not Yet Recruiting
3
Copenhagen University Hospital - Herlev and Gentofte, Herlev
Herlev, Denmark, 2730
Not Yet Recruiting
4
Copenhagen University Hospital - North Zealand, Hillerød
Hillerød, Denmark, 3400
Not Yet Recruiting
5
Copenhagen University Hospital - Amager and Hvidovre, Hvidovre
Hvidovre, Denmark, 2650
Actively Recruiting
6
University Hospital of Southern Denmark - Lillebælt Hospital, Kolding
Kolding, Denmark, 6000
Actively Recruiting
7
University Hospital of Southern Denmark - Odense University Hospital
Odense C, Denmark, 5000
Actively Recruiting
8
Zealand University Hospital
Roskilde, Denmark, 4000
Actively Recruiting
Research Team
A
Anneline B Seegert, MD
CONTACT
A
Anne J Wikkelsø, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here