Actively Recruiting
Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2026-01-21
60
Participants Needed
1
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the efficacy and safety of istent inject W in reducing intraocular pressure in Chinese adult patients with open-angle glaucoma complicated with cataract.
CONDITIONS
Official Title
Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Gender is not limited. Applicants must be 18 years old or above
- Diagnosed with open-angle glaucoma in the study eye
- Study eye has cataract meeting conditions for phacoemulsification
- Best corrected visual acuity of study eye is 40.7 or researcher-approved if better
- Normal opening angle of the study eye confirmed by angular endoscopy (Shaffer grade 3)
- No peripheral anterior iris adhesion, polycythemia, or abnormalities affecting stent placement
- Capable and willing to provide written informed consent and attend regular postoperative follow-ups
You will not qualify if you...
- Patients with angle-closure, pigmentary or pseudo-exfoliative glaucoma
- Patients with traumatic, malignant uveitis, neovascular or glaucoma related to vascular diseases
- Severe diabetic retinopathy, retinal detachment, retinal vein or artery occlusion, retinal degeneration, macular degeneration or edema affecting safety
- Congenital abnormalities of the anterior chamber angle
- Clinically significant corneal dystrophy, active inflammation, or prior surgery interfering with intraocular pressure measurement
- Retrobulbar tumors, thyroid eye disease, cavernous sinus fistula, Sturge-Weber syndrome or related conditions causing elevated venous pressure
- Eye or systemic diseases affecting surgical safety or examinations
- Pregnant or lactating women, women planning pregnancy or unable to use effective contraception during the study
- Failure to follow medical advice
- Other conditions deemed unsuitable by the researcher
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Eye Center, the 2nd Affiliated Hospital, Medical College of Zhejiang University
Hangzhou, China
Actively Recruiting
Research Team
K
Kaijun wang, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here