Actively Recruiting
Efficacy and Safety of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty
Led by Dezhou Hospital Qilu Hospital of Shandong University · Updated on 2024-08-16
60
Participants Needed
1
Research Sites
11 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if drug Bupivacaine liposomes works better than traditional peri-articular injection for Control of Pain in Total Knee Arthroplasty. It will also learn about the safety of drug Bupivacaine liposomes. The main questions it aims to answer are: Does Bupivacaine liposomes works better than traditional peri-articular injection for Control of Pain in Total Knee Arthroplasty. Researchers will compare Bupivacaine liposomes to traditional peri-articular injection to see if drug Bupivacaine liposomes works better for Control of Pain in Total Knee Arthroplasty Participants will: Receive peri-articular injection in total Knee Arthroplasty. checkups and tests During hospitalization.
CONDITIONS
Official Title
Efficacy and Safety of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female aged 18 years or older
- ASA classification of grade I-II
- Able to understand and communicate in Chinese and cooperate with examinations
- Scheduled for initial unilateral total knee arthroplasty under general anesthesia
- Willing to participate voluntarily and sign informed consent
You will not qualify if you...
- Use of other pain management methods before surgery
- Neuromuscular problems or other conditions affecting recovery in the operated limb
- Allergy or intolerance to any study drugs
- History of coronary artery disease, stent placement, deep vein thrombosis, pulmonary embolism, myocardial infarction, or ischemic stroke treated within past 6 months
- Serious liver or kidney dysfunction, coagulation disorders, cardiac arrhythmia, infection, or other surgery contraindications
- Neurological or psychiatric disorders affecting pain or study evaluation
- History of misuse or dependence on opioids, prescription drugs, illicit drugs, or alcohol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Qilu Hospital of Shandong University Dezhou Hospital (Dezhou People's Hospital)
Dezhou, Shandong, China, 250012
Actively Recruiting
Research Team
K
Ke Song
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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