Actively Recruiting
Efficacy and Safety of Local Glucocorticoids for the Treatment of Acute Radiation-Induced Intestinal Injury
Led by General Hospital of Shenyang Military Region · Updated on 2025-12-24
60
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Due to the increasing number and prolonged survival of malignant tumor patients treated with radiotherapy, the complication, such as acute radiation-induced intestinal injury, has become increasingly significant. Glucocorticoids may play a therapeutic role by regulating the inflammatory response in patients with acute radiation-induced intestinal injury. However, the conclusions of related studies were controversial.
CONDITIONS
Official Title
Efficacy and Safety of Local Glucocorticoids for the Treatment of Acute Radiation-Induced Intestinal Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Grade II-III acute radiation-induced rectosigmoid injury
- Signed informed consent
- Age 18 years or older
- Estimated survival time greater than 1 year
You will not qualify if you...
- Absolute contraindications to glucocorticoids
- Glucocorticoid treatment within the past 3 months
- Inflammatory bowel disease or infectious intestinal disease
- Recurrence of malignant tumor
- Colorectal cancer or metastasis
- Severe heart or lung diseases
- Recent history of surgery or trauma
- Poorly controlled hyperglycemia and hypertension
- Active tuberculosis
- Severe gastrointestinal ulcers
- Glaucoma
- Psychiatric diseases
- Pregnant or lactating
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area)
Shenyang, Liaoning, China, 110840
Actively Recruiting
Research Team
X
Xingshun Qi
CONTACT
Q
Qianqian Li
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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