Comparing Neuroendoscopic Surgery and Craniotomy for Large Brain Hemorrhage A Multicenter Randomized Study

What this Trial Is About

Researchers are evaluating the safety and effectiveness of neuroendoscopic surgery compared to traditional craniotomy for treating large intracerebral hemorrhage. This trial addresses the lack of prospective randomized studies on surgical methods for this condition, aiming to provide clearer guidance for treatment decisions. Previous studies suggest neuroendoscopic surgery may reduce surgery time and blood loss while improving recovery and quality of life. Participants will be randomly assigned to one of two groups one receiving neuroendoscopic surgery to remove the brain hematoma, and the other undergoing craniotomy for the same purpose. Both groups will receive standard medical care after surgery. The trial is conducted across multiple centers and includes a single-blinded design. During the study, participants will be monitored for several outcomes, including neurological recovery using the Modified Rankin Scale at 180 days, mortality rates at 30, 90, and 180 days, cognitive function with the Mini-Mental State Examination, and quality of life assessments. Researchers will also track hospital and ICU stay lengths, operation duration, and bleeding during surgery. Follow-up assessments will occur up to 180 days after treatment to evaluate safety and effectiveness.

Efficacy and Safety of NeuroEndoscopic Surgery for Large IntraCerebral Hemorrhage