Actively Recruiting
Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery
Led by The Fourth Affiliated Hospital of Zhejiang University School of Medicine · Updated on 2025-02-17
162
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial\] is to further explore the effectiveness and safety of oxelidine in the treatment of moderate to severe acute pain after orthopedic surgery. The main question it aims to answer is: Pain management after orthopaedic surgery provides more effective and safe drug options, provides new options for clinical treatment, and provides a scientific basis for clinical practice. Participants will be asked to pain score in the different time, treatments they'll be given and use optimal drug. Researchers will compare analgesic effect of oxelidine of different dose.
CONDITIONS
Official Title
Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Elective orthopedic surgery under general anesthesia
- Ability to communicate normally and express pain accurately
You will not qualify if you...
- Advanced tumor
- Other acute or chronic pain conditions
- Severe obesity (BMI 30 kg/m2 or higher)
- Pregnant or lactating women
- Allergy to opioids
- Sleep apnea syndrome
- Long-term opioid treatment
- Mental or nervous system diseases
- Gastrointestinal obstruction
- Chronic obstructive pulmonary disease or pulmonary heart disease
- Cardiovascular disease
- Abnormal liver function during screening
- Abnormal renal function during screening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Yiwu, Zhejiang, China, 322000
Actively Recruiting
Research Team
D
Dongmei Ma
CONTACT
L
Li Li
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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