Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT04043897

Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis

Led by Eugene F Yen, MD · Updated on 2021-04-15

10

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an open label study looking at rifaximin therapy for the treatment of microscopic (collagenous or lymphocytic) colitis.

CONDITIONS

Official Title

Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of collagenous colitis or lymphocytic colitis confirmed by colon biopsies reviewed by two pathologists
  • Collagenous colitis defined by a collagenous subepithelial table thicker than 10 micrometers with specific inflammation and epithelial changes
  • Lymphocytic colitis defined by more than 20 intraepithelial lymphocytes per 100 epithelial cells with specific inflammation and epithelial changes
  • Active flare with more than 3 watery or loose stools per day on more than 4 days out of 7 over more than 4 weeks within the past 3 months
Not Eligible

You will not qualify if you...

  • No specific exclusion criteria listed

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

NorthShore University HealthSystem

Evanston, Illinois, United States, 60201

Actively Recruiting

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Research Team

D

Daniel Amusin, BS

CONTACT

I

Iris Chiou, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis | DecenTrialz