Actively Recruiting
The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for Infraorbital Neuralgia
Led by Beijing Tiantan Hospital · Updated on 2025-02-21
240
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
B
Beijing Tiantan Hospital
Lead Sponsor
U
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a multicenter, prospective, observational, propensity score matching, cohort, and assessor-blinded study designed to compare the effectiveness and safety of PRP injections combined with PRF treatment with PRF alone in patients with IONa who are responded poorly to conventional therapies and are reluctant to receive destructive therapies for seeking a better minimally invasive treatment strategy.
CONDITIONS
Official Title
The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for Infraorbital Neuralgia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 to 75 years
- Paroxysmal or persistent stabbing pain in the infraorbital nerve area with positive response to diagnostic block (1 ml of 2% lidocaine) before treatment
- Numeric Rating Scale (NRS) pain score of 7 or higher
- Scheduled for pulsed radiofrequency treatment for infraorbital neuralgia
- Signed informed consent
You will not qualify if you...
- Platelet count below 105*10^9/L, ongoing anticoagulation or antiplatelet therapy, or bleeding disorders
- Severe heart, lung, liver, or kidney dysfunction
- Infection at the site of puncture
- Neuralgia caused by tissue damage near the infraorbital foramen from conditions like sinusitis or tumor
- Previous destructive treatments such as radiofrequency thermocoagulation, chemical ablation, infraorbital neurectomy, or nerve avulsion
- History of mental disorders
- History of narcotic drug abuse
- Unable to cooperate with the study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fang Luo
Beijing, Beijing Municipality, China, 100070
Actively Recruiting
Research Team
L
Lu Liu, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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