Actively Recruiting

Phase 3
Age: 18Years - 75Years
All Genders
NCT06880276

Efficacy and Safety Study of QLM3003 Ointment in Participants With Mild or Moderate Atopic Dermatitis

Led by Qilu Pharmaceutical Co., Ltd. · Updated on 2025-08-26

360

Participants Needed

1

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

It is a multicenter, randomized, double-blind, placebo-controlled, parallel-group phase 3 clinical trial to evaluate the efficacy of QLM3003 ointment at week 8 based on the primary endpoint (EASI 75) and key secondary endpoint (IGA-TS).in patients with mild to moderate atopic dermatitis. A total of 360 patients with mild to moderate atopic dermatitis are planned to be included and randomized at a ratio of 1:1:1 to receive 1.5% QLM3003 ointment、2% QLM3003 ointment and placebo, twice a day.

CONDITIONS

Official Title

Efficacy and Safety Study of QLM3003 Ointment in Participants With Mild or Moderate Atopic Dermatitis

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female, 18-75 years old
  • Diagnosis of atopic dermatitis meeting Hanifin-Rajka standards
  • History of atopic dermatitis or eczema for at least 1 year before screening
  • Investigator's Global Assessment (IGA) score of 2 or 3
  • Atopic dermatitis involving head and neck (excluding scalp), trunk, and limbs
  • Total affected body surface area (BSA) between 3% and 20% inclusive
Not Eligible

You will not qualify if you...

  • Other medical conditions that could interfere with study assessments as judged by the investigator
  • Unstable atopic dermatitis with spontaneous improvement or rapid worsening
  • Use of marketed or investigational biologics for atopic dermatitis within 3 months or 5 half-lives before baseline
  • Use of systemic or topical JAK inhibitors within 4 weeks or 5 half-lives before baseline

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of China Medical University

Shenyang, China

Actively Recruiting

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Research Team

M

Mingxia Lv, Master

CONTACT

X

Xinghua Gao, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Efficacy and Safety Study of QLM3003 Ointment in Participants With Mild or Moderate Atopic Dermatitis | DecenTrialz