Actively Recruiting
The Efficacy and Safety of the Supraglottic Oxygenation Via Nasotracheal Intubation for Deep Sedation Fiberoptic Bronchoscopy
Led by First Affiliated Hospital of Zhejiang University · Updated on 2026-02-05
50
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Bronchoscopy is now widely used for the diagnosis and treatment of various respiratory diseases. However, the procedure is highly stimulating and provokes a strong stress response; because the airway is shared, patients are prone to hypoxia. With the growing emphasis on comfortable care, demand for anesthesia during bronchoscopy has increased. Deep sedation is the most common approach, but when administered in the supine position it often causes the tongue base to fall back. Both nasopharyngeal and oropharyngeal airways can relieve this obstruction, yet neither connects seamlessly to an oxygen supply line, resulting in insufficient oxygen delivery.We therefore replaced the nasopharyngeal airway with a wired endotracheal tube (size 4.0 or 4.5) inserted via the nose. This thinner tube couples easily to an oxygen line or ventilator circuit, partially relieves airway obstruction, and allows ample supraglottic oxygenation. The present study was designed to evaluate the feasibility and safety of this modified oxygen-delivery method in patients undergoing deep sedation for bronchoscopy.
CONDITIONS
Official Title
The Efficacy and Safety of the Supraglottic Oxygenation Via Nasotracheal Intubation for Deep Sedation Fiberoptic Bronchoscopy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Undergoing fiberoptic bronchoscopy under deep sedation.
- Written informed consent obtained from the patient or their legal representative.
- Clear understanding of, and voluntary participation in, the study, with informed-consent form signed by the patient or their legal representative.
You will not qualify if you...
- Age under 18 years.
- Body mass index (BMI) over 30 kg/m².
- Previous history of abnormal recovery from anesthesia or surgery.
- History of recurrent nosebleeds, nasal bone fracture, nasal polyps, or sinus surgery.
- Chronic use of opioid analgesics, benzodiazepine hypnotics, or antidepressant medications.
- Known allergy to any anesthetic agents used.
- Anticipated difficult airway.
- Increased intracranial pressure.
- Active upper respiratory infection in the oral, nasal, or pharyngeal areas.
- Severe heart failure with functional capacity less than 4 METs.
- Severe kidney failure requiring dialysis before surgery.
- Pre-operative oxygen saturation on room air below 92%.
- Any condition that makes the patient unsuitable for the trial according to the investigator.
AI-Screening
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Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Zhejiang University
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
Y
Yueying Zheng
CONTACT
Y
Yeke Zhu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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