Actively Recruiting
Efficacy and Safety of Upadacitinib in Inflammatory Bowel Disease
Led by Xiang Gao · Updated on 2025-01-17
174
Participants Needed
6
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Inflammatory Bowel Disease (IBD), which encompasses ulcerative Colitis (UC) and Crohn's Disease (CD), has seen significant improvements in patient outcomes with biologic treatments. However, nearly half of the patients are either primary or secondary non-responders to the existing biologics. Upadacitinib is the only oral small molecule targeted drug approved for IBD in China. There is a paucity of research on the efficacy and safety of upadacitinib in treating Chinese patients with UC and CD, and a lack of study data on the Chinese IBD population. This study aims to conduct a multicenter, single-arm, prospective, observational real-world study to analyze the efficacy and safety of upadacitinib in the treatment of Chinese patients with IBD, providing a basis for clinical decision-making.
CONDITIONS
Official Title
Efficacy and Safety of Upadacitinib in Inflammatory Bowel Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of any gender diagnosed with ulcerative colitis or Crohn's disease according to current guidelines
- Patients who require initial treatment with upadacitinib as decided by their physician
- Patients who provide signed informed consent to participate
You will not qualify if you...
- Current or planned participation in any other clinical study
- Contraindications to upadacitinib treatment as specified in the drug instructions
- Patients considered unsuitable for the study by the researchers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Guangzhou, Guangdong, China, 510000
Actively Recruiting
2
Sixth Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China, 510655
Actively Recruiting
3
Meizhou People's Hospital
Meizhou, Guangdong, China, 514000
Actively Recruiting
4
The Eighth Affiliated Hospital, Sun Yat-Sen University
Shenzhen, Guangdong, China, 518000
Actively Recruiting
5
Liuzhou People's Hospital
Liuzhou, Guangxi, China, 545000
Actively Recruiting
6
Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine
Nanning, Guangxi, China, 530000
Actively Recruiting
Research Team
L
Lang Lin
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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