Actively Recruiting

Phase Not Applicable
Age: 14Years +
All Genders
NCT06692296

Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia

Led by IRCCS Eugenio Medea · Updated on 2025-05-02

24

Participants Needed

1

Research Sites

147 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary objective is to evaluate the potential effectiveness of an individualized intensive rehabilitation intervention using the "Prokin 252" stabilometric platform in the treatment of adolescent and adult patients with Friedreich's Ataxia. The secondary objective is to assess the retention of the rehabilitation treatment effects over time. Enrolled patients will be randomized and assigned to one of two treatment groups for four weeks. Three assessments will be conducted for each patient: one before treatment (T0), one at the end of treatment (T1), and a follow-up assessment 90 days after T1 via telemedicine (T2). This study is: * Exploratory: The study aims to explore the usefulness of the stabilometric platform in a rehabilitative setting in combination with conventional therapy; * Not "first-in-human"; * Longitudinal: The study will investigate changes over time in motor and functional ability scales, as well as stabilometric platform parameters, within the same cohort; * Randomized, controlled, open-label; * Monocentric: The study will be conducted only at the "La Nostra Famiglia" Association in Conegliano and Pieve di Soligo - IRCCS Eugenio Medea in Conegliano - UOC Neuromotor Rehabilitation in Pieve di Soligo, Via Monte Grappa, 96, 31053 Pieve di Soligo TV; * Prospective; * Post-market.

CONDITIONS

Official Title

Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia

Who Can Participate

Age: 14Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 14 years or older
  • Weight less than 150 kg
  • Genetic diagnosis of Friedreich's Ataxia
  • Score between 1 to 6 on 'Gait' item of SARA scale
  • Score between 1 to 3 on 'Stance' item of SARA scale
  • Ability to walk at least 10 meters with or without walking aids
  • Ability to stand unsupported
  • Friedreich Ataxia Rating Scale stage between 2 and 4
Not Eligible

You will not qualify if you...

  • Younger than 14 years
  • Diagnosis of acquired ataxia
  • Score of 0 or 7 on 'Gait' item of SARA scale
  • Score of 0 or 4 to 6 on 'Stance' item of SARA scale
  • Inability to walk
  • Ability to walk less than 10 meters
  • Can only stand with support
  • Other neurological conditions
  • Current major psychiatric disorder such as psychosis or major depression

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Scientific Institute, IRCCS E. Medea, Department of Pieve di Soligo, Treviso, Italy

Pieve di Soligo, Veneto, Italy, 31053

Actively Recruiting

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Research Team

G

Gabriella Paparella, Medical Degree

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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