Actively Recruiting
Efficacy of Statins Among Major Depressive Disorder
Led by Ain Shams University · Updated on 2025-08-17
145
Participants Needed
1
Research Sites
169 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if drug Rosuvastatin 10 mg works to treat MDD in adults. It will also learn about the safety of Rosuvastatin 10 mg .The main questions it aims to answer are: Does Rusovastatin lower the score of The Montgomery Asberg Depression Rating Scale (MADRS) among adult participants with Major Depression Disorder ( MDD )? What medical problems do participants have when taking drug ABC? Participants will: Take Rosuvastatin 10 mg every day for 3 months Visit the clinic once every 4 weeks for checkups and tests Report any side effects for Rosuvastatin 10 mg and reassess the severity of depression using The Montgomery Asberg Depression Rating Scale (MADRS)
CONDITIONS
Official Title
Efficacy of Statins Among Major Depressive Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 20 and 45 years
- Diagnosis of current Major Depressive Disorder confirmed using Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I/P)
- Montgomery Asberg Depression Rating Scale (MADRS) score between 7 and 34 indicating mild to moderate depression
- Ability to give informed consent and comply with study procedures
- Both males and females
- Stable pharmacological treatment for at least 2 weeks before enrollment if currently treated, except dose or frequency changes
You will not qualify if you...
- Lifetime or current diagnosis of psychotic disorder
- Lifetime diagnosis of bipolar I or II disorder or alcohol dependence
- Acute or unstable systemic medical condition
- Inability to comply with informed consent or study protocol
- History of intolerance or allergy to study medications
- Current pregnancy or breastfeeding
- Current regular use of statins, corticosteroids, or other immunomodulatory agents
- Females using contraception
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
El demerdash hospital
Cairo, Al Abbasia, Egypt, +02
Actively Recruiting
Research Team
S
Silvana Nader
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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