Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06599086

Efficacy of Steroid Injection in Patients With Bifid Median Nerve Diagnosed Carpal Tunnel Syndrome

Led by Yunus Burak Bayır · Updated on 2025-05-30

40

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Various median nerve anatomical variations have been reported in the literature.One of these is the bifid median nerve.Due to its relatively higher cross-sectional area, it can facilitate compression of the median nerve in the carpal tunnel.Therefore, bifid median nerve is relatively common in patients with CTS.Some studies have shown that the bifid median nerve has an effect on surgical failure in the treatment of carpal tunnel syndrome.Apart from surgical treatment, perineural injection with corticosteroids is a treatment method that has been used for a long time in the treatment of mild and moderate carpal tunnel syndrome.It is controversial whether bifid median nerve has a negative effect on treatment effectiveness.When looking at the literature, there is no previous study on this subject.With the introduction of ultrasound into our daily practice, the frequency of ultrasound-guided perineural injections has increased.Ultrasound allowed us to see variations in the median nerve before injection.The aim of the study is to compare the effectiveness of steroid injection in patients with CTS with bifid median nerve and patients with CTS with non-variant median nerve.It is also to investigate whether this anatomical variation has a negative effect on the treatment.

CONDITIONS

Official Title

Efficacy of Steroid Injection in Patients With Bifid Median Nerve Diagnosed Carpal Tunnel Syndrome

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • Clinical diagnosis of Carpal Tunnel Syndrome
  • Mild or moderate Carpal Tunnel Syndrome confirmed by EMG
  • Bifid median nerve diagnosed by ultrasound; control group has no variation
  • Typical Carpal Tunnel Syndrome symptoms for at least 3 months
Not Eligible

You will not qualify if you...

  • History of polyneuropathy, brachial plexopathy, thoracic outlet syndrome, or wrist surgery
  • History of inflammatory arthritis, hypothyroidism, pregnancy, rheumatological disorders, or heart battery
  • Current use of warfarin
  • Prior steroid injection for Carpal Tunnel Syndrome
  • Trauma or neoplasm at the injection site
  • Hypersensitivity to corticosteroids or skin infection at the injection site
  • Presence of other median nerve variations or persistent median artery

AI-Screening

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Trial Site Locations

Total: 1 location

1

Etlik City Hospital

Ankara, Ankara, Turkey (Türkiye), 06170

Actively Recruiting

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Research Team

Y

YUNUS BURAK BAYIR, SPECİALİST

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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