Actively Recruiting
Efficacy of Surgical Glove-Compression Therapy As a Prevention of Paclitaxel-Induced Peripheral Neuropathy
Led by Department of Medical Services Ministry of Public Health of Thailand · Updated on 2025-01-08
36
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this randomized controlled trial (RCT) is to compare the incidence of paclitaxel-induced grade 2 or higher sensory peripheral neuropathy, evaluated using the CTCAE version 5.0, between patients receiving surgical glove-compression therapy (SGCT) and those in the control group. The main question is whether SGCT is effective in preventing paclitaxel-induced sensory peripheral neuropathy. * Intervention group: receive SGCT. * Control group: receive non-compressive plastic gloves.
CONDITIONS
Official Title
Efficacy of Surgical Glove-Compression Therapy As a Prevention of Paclitaxel-Induced Peripheral Neuropathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed Informed Consent Form
- Age 18 years or older at the time of signing Informed Consent Form
- Patients with any pathological diagnosis of solid tumor, such as breast cancer or lung cancer
- Patients scheduled to be receiving intravenous paclitaxel or paclitaxel-based regimen every 3 weeks
You will not qualify if you...
- Patients who received chemotherapeutic agents that could cause neuropathy, such as taxane-based or platinum-based chemotherapy and anti-microtubule agents
- History of neuropathy
- History of carpal tunnel syndrome
- History of allergic reactions to latex or gloves
- Patients receiving treatments that may treat neuropathy, such as amitriptyline, gabapentin, Acetyl L-Carnitine, Ganglioside-monosialic acid, acupuncture, cryotherapy, or exercise therapy
- History of Raynaud phenomenon
- History of wounds or large scars on hands
- Pregnancy or breastfeeding
- History of poorly controlled diabetes with HbA1c greater than 6.5
AI-Screening
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Trial Site Locations
Total: 1 location
1
Rajavithi Hospital, Medical Oncology Unit
Bangkok, Bangkok, Thailand, 10400
Actively Recruiting
Research Team
S
Saowani Thantaviraya, M.D.
CONTACT
S
Sunatee Sa-nguansai, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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