Comparing SynEx Wound Cleanser to Saline for Healing Civilian Gunshot, Penetrating, and Burn Wounds

What this Trial Is About

This clinical trial studies wound healing in participants with traumatic wounds such as gunshot, penetrating, puncture, or burn wounds of the upper or lower extremities. The purpose is to compare the effects of SynEx Wound Cleanser, a device containing patented chitosan derivatives, with the current routine care using saline solution. The study aims to understand how these cleansers influence the wound healing environment over a 14-day period. Participants are randomly assigned to one of two groups one group uses SynEx Wound Cleanser, which is reconstituted in water and applied as directed by a healthcare provider, while the other group uses a saline solution for wound cleansing. The study involves up to four visits where participants will use their assigned cleanser and provide feedback through brief surveys about their wound healing and well-being. During the study, participants will attend scheduled visits to have their wounds assessed and to complete surveys related to healing progress and overall health. Researchers will measure the wound healing environment composite score after 14 days to evaluate treatment effects. Participants must have access to a computer or mobile device for telepresence visits and be willing to follow all study procedures. The study will continue until September 2025.

Efficacy of SynEx Wound Rinse in Civilian Surrogates of Combat Injury Wounds