Actively Recruiting
Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression
Led by Tianjin Anding Hospital · Updated on 2026-02-27
100
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to evaluate the feasibility and efficacy of deep transcranial magnetic stimulation (dTMS) as an add-on treatment for bipolar depression. Meanwhile, we aim to evaluate the effect of dTMS on cognitive function of bipolar depressive patients. We hypothesize dTMS would improve depressive symptoms and cognitive function in bipolar disorder.
CONDITIONS
Official Title
Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of bipolar depression
- Age between 18 and 65 years
- Hamilton Depression Rating Scale (HDRS-17) score of 17 or higher
- Stable medication regimen maintained for at least 4 weeks before treatment
- Minimum 4-week washout period and re-evaluation for those previously on antidepressants
You will not qualify if you...
- History of other psychiatric disorders, neurological diseases, or severe brain injury
- Received electroconvulsive therapy, rTMS, transcranial direct or alternating current stimulation, or other neurostimulation treatments within last 3 months
- Contraindications to magnetic stimulation such as epilepsy, cardiovascular disorders, or metal implants in the head
- Presence of hypomanic or manic symptoms at baseline or Young Mania Rating Scale (YMRS) score over 12
- Pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tianjin Anding Hospital
Tianjin, China
Actively Recruiting
Research Team
J
Jie Li, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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