Actively Recruiting
Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
Led by Albert Einstein College of Medicine · Updated on 2025-05-22
46
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the safety and effectiveness of a hybrid fractional laser to treat acne scars, especially in patients with darker skin tones (Fitzpatrick IV and V). Acne scarring, often caused by skin damage during healing, can negatively affect quality of life and mental health. Current treatments struggle with effectiveness and safety in skin of color, prompting this study to focus on a hybrid laser combining ablative and non-ablative components. The study involves two groups based on skin type: one with Fitzpatrick IV-V and another with Fitzpatrick I-III. Each participant receives up to three sessions of the Sciton Halo hybrid fractional laser, which uses two wavelengths to target different skin layers. Before treatment, participants receive education on the procedure and sun care, and may be prescribed hydroquinone or retinol to reduce the risk of hyperpigmentation. Treatment sessions include before and after photos, and participants complete surveys on quality of life and satisfaction. Participants will be involved for about eight months, with assessments at multiple points including baseline, 3, 5, and 8 months. These assessments measure changes in acne scar severity, patient satisfaction, and dermatology quality of life using standardized surveys. The study monitors tolerability and outcomes throughout, ensuring participants follow the treatment and follow-up schedule. The research aims to improve understanding of hybrid laser treatment effects in skin of color.
CONDITIONS
Brief Title
Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy males and females 18 years of age or older
- Seeking treatment for acne scarring
- Diagnosis of acne scarring recorded within the past 6 months
- Able to read, understand, and voluntarily provide written informed consent
- Healthy non-smoker
- Able and willing to comply with treatment protocol and follow-up schedule
- Agrees not to undergo other procedures in the treatment areas during follow-up period
You will not qualify if you...
- Unable to provide informed consent
- Acne scar treatments within 6 months prior to enrollment
- Active papulopustular or cystic acne within past 6 months
- History of keloidal scarring
- Surgical procedures in the treatment area within past 12 months or major surgery in past 6 months
- History of immunosuppression, immune deficiency, or systemic chemotherapy in past 12 months
- Use of immunosuppressive medications or biologics within 6 months prior to and during study
- Use of Accutane or systemic retinoids in past 12 months
- Smoking or vaping in past 12 months
- History of photosensitivity or connective tissue disease
- History of hyperlipidemia, diabetes, hepatitis, or bleeding disorders
- History of major depressive or endocrine disorders including hypothyroidism, Hashimoto's thyroiditis, or hyperthyroidism
- Current pregnancy, active breastfeeding, cancer, or epilepsy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 month
Participants prescribed hydroquinone or retinol wait one month before beginning treatment.
1 visit (in-person) for prescription and education
Duration - Variable, depending on degree of improvement
Participants receive up to 3 sessions of hybrid fractional laser treatment with Sciton Halo. Before and after images are taken and surveys on quality of life and satisfaction are completed at each session.
3 treatment visits (in-person)
Duration - Up to 8 months after baseline
Participants complete surveys on acne scar severity, quality of life, and satisfaction through approximately 8 months after baseline.
Visits at months 3, 5, and 8 for assessments
Trial Site Locations
Total: 1 location
1
555 Taxter Road
Elmsford, New York, United States, 10523
Actively Recruiting
Research Team
A
Anika Jallorina, BS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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