Actively Recruiting
Efficacy of Trans-auricular Vagus Nerve Stimulation on Upper Extremity Motor Recovery in Stroke Survivors
Led by Universidade Federal de Pernambuco · Updated on 2026-05-04
30
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
Sponsors
U
Universidade Federal de Pernambuco
Lead Sponsor
F
Fundação de Amparo à Ciência e Tecnologia de Pernambuco
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this clinical trial is to determine if trans-auricular vagus nerve stimulation (taVNS) is effective in improving upper extremity function in stroke survivors. The primary objectives include: Investigating whether taVNS improves motor function in stroke survivors. The secondary objectives include: Assessing any potential side effects associated with the method. Investigating taVNS effects on daily routine functions and spasticity Researchers will conduct a comparative analysis between taVNS and a sham procedure (which mimics the stimulation without any actual effect) to assess its effectiveness. Participants in the trial will: Undergo taVNS combined with physical therapy or a sham procedure with physical therapy daily over a two-week period.
CONDITIONS
Official Title
Efficacy of Trans-auricular Vagus Nerve Stimulation on Upper Extremity Motor Recovery in Stroke Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged between 18 and 75 years
- Motor impairment in the upper extremity caused by unilateral ischemic or hemorrhagic stroke
- Stroke onset within the last five years
You will not qualify if you...
- Contraindication to trans-auricular vagus nerve stimulation (taVNS)
- Peripheral upper extremity injuries
- Use of medication affecting cortical excitability in the past 3 months
- Use of botulinum toxin in the past 3 months
- Presence of any other neurological disorder
- Significant cognitive deficits
AI-Screening
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Trial Site Locations
Total: 1 location
1
Federal University of Pernambuco
Recife, Pernambuco, Brazil, 50670-901
Actively Recruiting
Research Team
D
DANIEL G DE MELO, MsC
CONTACT
G
Gabriel Barreto, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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