Actively Recruiting

Phase Not Applicable
Age: 12Years - 21Years
All Genders
NCT06919432

Efficacy of Triple-daily 15mA tACS on Adolescent NSSI

Led by Shanghai Mental Health Center · Updated on 2025-06-12

66

Participants Needed

1

Research Sites

126 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In order to assess the clinical efficacy of triple-daily 15mA-tACS stimulation by comparing the effects of active and sham tACS interventions on driving improvements in adolescent Nonsuicidal Self-Injury(NSSI), participants will be randomly assigned to either the active or sham tACS group. This trial consists of a 2-week intensified intervention phase (40 sessions), followed by a 4-week observation period. The key hypothesis is that triple-daily 15mA-tACS stimulation will enhance clinical recovery compared to sham stimulation.

CONDITIONS

Official Title

Efficacy of Triple-daily 15mA tACS on Adolescent NSSI

Who Can Participate

Age: 12Years - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of NSSI based on DSM-5 criteria section 3
  • Five or more NSSI episodes in the past year and at least one episode in the past month
  • Age between 12 and 21 years
  • Informed consent from parents or legal guardians
  • Informed consent from participants aged 15 years and above
Not Eligible

You will not qualify if you...

  • Current or history of organic brain or neurological disorders
  • Elevated or imminent suicidal risk
  • Previous or current exposure to ECT, modified ECT, TMS, tDCS, tACS, or other neurostimulation treatments
  • Presence of cochlear implants, cardiac pacemakers, implanted devices, or metal in the brain
  • Previous or current use of psychotropic medication
  • Pregnancy or lactation
  • Participation in another clinical trial
  • Refusal to provide informed consent
  • Other conditions deemed unsuitable by researchers

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Shanghai Mental Health Center

Shanghai, Shanghai Municipality, China, 200030

Actively Recruiting

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Research Team

T

TianHong Zhang, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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