Actively Recruiting
Efficacy of Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy
Led by Bengu Turemenogullari · Updated on 2025-04-09
66
Participants Needed
1
Research Sites
89 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main symptom of knee osteoarthritis, which occurs after damage to the joint cartilage with age, is pain, but this symptom often becomes chronic. Current conservative treatments have moderate effects on chronic knee pain and their use is limited due to the risk of side effects. In addition to pain, patients also experience other symptoms. As a result of the osteoarthritis process, prorioception in the knee is impaired with a decrease in mechanoreceptors, resulting in loss of balance and an increase in the risk of falling.
CONDITIONS
Official Title
Efficacy of Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 30 and 75 years
- Chronic knee pain lasting at least 6 months
- Radiographic confirmation of osteoarthritis with Grade 3 or 4 changes showing significant narrowing in the medial tibiofemoral joint space
- Knee pain greater than 40 mm on a 100 mm visual analog scale during sitting to standing or stair climbing
- At least 50% reduction in pain after diagnostic genicular nerve block
You will not qualify if you...
- Presence of systemic inflammatory diseases like rheumatoid arthritis
- Previous radiofrequency ablation treatment or knee steroid/hyaluronic acid injections within the last 3 months
- History of previous knee surgery
- Significant structural knee abnormalities other than osteoarthritis causing chronic pain
- Physical therapy to the knee in the last 6 months or history of knee trauma
- Current use of other pain treatments
- Body mass index below 18 or above 40 kg/m2
- Pregnancy
- Uncontrolled serious illnesses such as cancer or diabetes, infection, psychiatric disorders, or coagulation disorders
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Ankara Etlik City Hospital, Physical Medicine and Rehabilitation
Ankara, Ankara, Turkey (Türkiye)
Actively Recruiting
Research Team
B
Bengu Turemenogullari
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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