Study of Midurethral Sling Treatments for Women Aged 30 to 100 With Stress Urinary Incontinence

What this Trial Is About

Researchers are evaluating the bladders voiding function response after surgery with midurethral slings, such as the trans-obturator tape TOT, in women diagnosed with stress urinary incontinence SUI. The study aims to clarify whether the bladders thermodynamic efficiency changes following the TOT procedure, which is known for its effective cure rate and less invasive approach. Participants undergo urodynamic investigations including free uroflowmetry, postvoid residual measurements, filling and voiding cystometry, and urethral pressure profiles. These tests are conducted both before and 4-6 weeks after the TOT surgery, using saline at body temperature infused at a controlled rate. Data are analyzed to compare bladder function parameters such as maximum flow rate and detrusor pressure during voiding cycles. During the study, participants receive comprehensive urodynamic evaluations one to four weeks before surgery and again at a follow-up visit 4-6 weeks post-operation. The research team monitors various bladder function indicators and analyzes the pressure-volume relationship within voiding cycles to assess changes. This observational timeline helps determine the safety and efficacy of midurethral slings in improving bladder continence and function over time.

Efficacy/Safety of Midurethral Sling