Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06410664

Efficiency and Safety of the Prolonged Use of Heat and Moisture Exchangers in ICU

Led by Charles University, Czech Republic · Updated on 2024-07-26

120

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

FILTRex is a single-centre, controlled, randomised, prospective, non-inferiority clinical trial to compare the efficiency and safety of prolonged (72-hours) versus standard (24-hours) duration of use for Heat and Moisture Exchange (HME) filters in adult mechanically ventilated critically ill patients

CONDITIONS

Official Title

Efficiency and Safety of the Prolonged Use of Heat and Moisture Exchangers in ICU

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Admitted as an ICU in-patient with expected stay longer than 3 days
  • Currently on mechanical ventilation or expected to need it for 72 hours or more
  • Clinical Pulmonary Infection Score less than 6 at baseline
  • No history or symptoms of aspiration at baseline
Not Eligible

You will not qualify if you...

  • Suspected lung infection at admission or within first 48 hours of mechanical ventilation
  • Pregnancy
  • Acute respiratory distress syndrome
  • Body temperature below 32°C
  • Airway bleeding or other reasons preventing use of HME
  • Early decision to withdraw treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

3rd Faculty of Medicine and FNKV

Prague, Česká Republika, Czechia, 110 00

Actively Recruiting

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Research Team

Š

Šárka Línková

CONTACT

A

Adéla Jiroudkova

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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