Actively Recruiting
EGb 761 in the Syndrome of MCI With Concomitant CVD
Led by National Neuroscience Institute · Updated on 2022-11-17
134
Participants Needed
1
Research Sites
313 weeks
Total Duration
On this page
Sponsors
N
National Neuroscience Institute
Lead Sponsor
D
Dr. Willmar Schwabe GmbH & Co. KG
Collaborating Sponsor
AI-Summary
What this Trial Is About
EGb 761 has been demonstrated to be useful in improving cognitive and global clinical outcomes in patients with cognitive impairment or dementia, when administered at a daily dosage of 240mg in randomised controlled trials through several neuroprotective mechanisms of action. The study aims to determine the efficacy and safety profile of EGb 761 as a prescribed clinical drug for patients with MCI + CVD.
CONDITIONS
Official Title
EGb 761 in the Syndrome of MCI With Concomitant CVD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with mild cognitive impairment based on the Petersen and Albert MS criteria
- Global Clinical Dementia Rating Score of 0.5
- Aged 45 to 85 years at study entry
- Literate and able to complete cognitive evaluations per investigator opinion
- Presence of cerebrovascular disease confirmed by white matter hyperintensities of Fazekas grade 2 or 3 on MRI or CT scans done within 12 months prior to recruitment
- Provided written informed consent to participate
You will not qualify if you...
- Receiving antidepressants, antipsychotics, benzodiazepines, acetylcholinesterase inhibitors, or NMDA antagonists during the study
- Contraindications for EGb 761 as per local prescribing information or Summary of Product Characteristics (SmPC)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Neuroscience Institute
Singapore, Singapore, 308433
Actively Recruiting
Research Team
J
Joanna Wang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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