Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05427240

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Led by Abramson Cancer Center at Penn Medicine · Updated on 2026-01-16

1000

Participants Needed

1

Research Sites

196 weeks

Total Duration

On this page

Sponsors

A

Abramson Cancer Center at Penn Medicine

Lead Sponsor

F

Fox Chase Cancer Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

This randomized non-inferiority study will use a 2x2 design where traditional standard-of-care pre-test (visit 1) and post-test (visit 2: disclosure) counseling delivered by a genetic counselor are replaced with a self-directed web-based eHealth intervention to provide critical data to inform optimal ways to deliver clinical genetic testing in eligible individuals, while maintaining quality of care and favorable cognitive, affective and behavioral outcomes.

CONDITIONS

Official Title

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Speak and understand English
  • Male or Female
  • No prior germline genetic testing
  • Meet current National Comprehensive Cancer Network (NCCN) guidelines for germline genetic testing
Not Eligible

You will not qualify if you...

  • Uncorrected or uncompensated hearing and/or vision impairment
  • Uncorrected or uncompensated speech defects
  • Uncontrolled psychiatric or mental condition
  • Severe physical, neurological, or cognitive deficits preventing understanding of study goals and tasks

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Abramson Cancer Center at the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

A

Angela R Bradbury, MD

CONTACT

D

Dominique Fetzer, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

4

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