Actively Recruiting
EIT Assessment of Overdistension in ARDS Patients in Prone Position
Led by University Hospital, Bordeaux · Updated on 2026-01-15
20
Participants Needed
2
Research Sites
80 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Mechanical ventilation in ARDS requires protective ventilation with low VT and PEEP. PEEP titration can improve lung recruitment in the dependent lung but with a risk of overdistension in the non-dependant lung. EIT can measure the distribution of tidal ventilation and assess overdistension and collapse during a PEEP titration in any position (prone or not). This study aims to measure the best PEEP as a compromise between recruitment and overdistension during a PEEP trial with EIT before and just after PP.
CONDITIONS
Official Title
EIT Assessment of Overdistension in ARDS Patients in Prone Position
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hospitalized in ICU with moderate or severe ARDS (Berlin criteria, PaO2/FiO2 <150)
- Intubated, sedated, and receiving muscle relaxants
- Equipped with Electrical Impedance Tomography (EIT)
- Aged 18 years or older
You will not qualify if you...
- Broncho-pleural leaks
- Pregnant or breastfeeding
- Under guardianship or curatorship
- Deprived of liberty
- No health insurance
- Unable to correctly position the EIT belt (e.g., due to dressings or chest drainage)
- Contraindications to EIT (e.g., implantable cardiac defibrillator, pacemaker, unstable spinal lesions)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
CH Cote Basque
Bayonne, France, 64000
Actively Recruiting
2
Hopital Haut-Lévêque
Pessac, France, 33604
Actively Recruiting
Research Team
B
Benjamin REPUSSEAU, Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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