A Study Comparing EIT-Guided Individualized PEEP Versus Standard Fixed PEEP Ventilation to Prevent Lung Complications After Laparoscopic Bariatric Surgery in Adults Aged 18 to 65

What this Trial Is About

Researchers are evaluating the use of electrical impedance tomography EIT to guide individualized positive end-expiratory pressure PEEP settings during laparoscopic bariatric surgery. This randomized controlled trial aims to compare EIT-guided PEEP with a fixed PEEP value of 8 cmH2O to see if it reduces the incidence of postoperative pulmonary complications within 72 hours after surgery. The study is conducted at a single center and includes adults undergoing gastric sleeve resection with obesity-related conditions. Participants will be randomly assigned to one of two groups. The EIT-guided group will receive ventilation adjusted by EIT measurements through a recruitment maneuver and decremental PEEP titration after intubation, maintaining individualized PEEP throughout surgery. The control group will receive standard ventilation with a fixed PEEP of 8 cmH2O and volume-controlled ventilation settings. Both groups will undergo recruitment maneuvers at specific times during the procedure. During the study, participants will be monitored for lung function using lung ultrasound scores at several postoperative time points and arterial blood gas analysis during surgery. Researchers will track the occurrence and severity of pulmonary complications up to 72 hours after surgery. The trial includes detailed assessments to evaluate respiratory status and safety, with participation lasting from preoperative preparation through the immediate postoperative period.

EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery