Actively Recruiting
EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery
Led by Jianbo Wu · Updated on 2025-10-06
118
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a prospective, single-center, single-blind, randomized controlled clinical trial. Patients scheduled for laparoscopic bariatric surgery will be selected and randomly assigned to either the EIT-guided individualized PEEP group (Group P-eit) or the control group (Group P-8). Group P will be ventilated using the PEEP value determined by EIT, while Group C will be ventilated with a fixed PEEP value of 8 cmH2O.The primary outcome is the incidence of postoperative pulmonary complications (PPCs) within 72 hours after surgery.
CONDITIONS
Official Title
EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Scheduled for laparoscopic bariatric surgery under general anesthesia
- American Society of Anaesthesiologists (ASA) physical status I to III
- Body mass index (BMI) between 30 and 55 kg/m2
- Voluntarily agree to participate and sign informed consent form
You will not qualify if you...
- History of smoking or previous thoracic surgery
- Use of invasive mechanical ventilation within the past 30 days
- Pregnancy
- Allergy to EIT electrodes
- Persistent hemodynamic instability or refractory shock
- Severe cardiopulmonary disease such as severe COPD, NYHA Class III or IV, acute coronary syndrome, or sustained ventricular tachycardia
- Severe pulmonary hypertension with systolic pulmonary artery pressure over 40 mmHg
- Conditions like increased intracranial pressure, intracranial injury or tumor, or neuromuscular disorders
- Conversion to open surgery (laparotomy)
- Planned transfer to intensive care unit after surgery
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital
Jinan, Shandong, China, 0531
Actively Recruiting
Research Team
J
Jian bo Wu, PH.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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