What is this study trying to find out about complications after hip and knee replacement surgery?

This study is investigating whether using medication alone to prevent blood clots is as effective as using medication together with elastic compression restraints after hip or knee replacement surgery. Researchers want to understand if the elastic restraints are still necessary when rehabilitation programs have improved. The study is sponsored by Clinique Pasteur Lanroze and aims to improve patient care after surgery.

Who may be eligible for this arthroplasty complications clinical trial?

Adults aged 18 years or older who have had a first line, non-traumatic total hip or knee arthroplasty and are participating in an Enhanced Rehabilitation after Surgery or fast-track protocol may be eligible. People with certain medical conditions like clotting disorders or those on long-term anticoagulation are excluded. Please review eligibility criteria for more details.

Is there any cost to participate in this arthroplasty complications clinical trial?

Study-related care, including the study drug or procedure and all trial visits, is provided at no cost. However, personal travel expenses may vary and are not guaranteed to be covered. Participants should consider their own travel arrangements when planning to join.

Actively Recruiting

Phase Not Applicable

Age: 18Years +

All Genders

ID06563531

Are Elastic Restraints Still Necessary in Improved Rehabilitation Programs After Hip and Knee Prosthetic Surgery?

Led by Clinique Pasteur Lanroze · Updated on 2026-04-06

1274

Participants Needed

Research Sites

4 weeks

Total Duration

AI-Summary

What this Trial Is About

This research aims to evaluate the necessity of elastic restraints in preventing venous thrombosis and pulmonary embolism after hip and knee replacement surgery. These serious complications can be potentially prevented, but the benefits of using elastic compression devices alongside pharmacological treatment remain unclear. The study investigates whether using medication alone is as effective as combining medication with elastic restraints in these surgeries. Participants will be randomly assigned to one of two groups: one receiving pharmacological thromboprophylaxis combined with elastic compression restraints, and the other receiving only pharmacological thromboprophylaxis without elastic compression. The study will assess outcomes up to 90 days after prosthetic surgery to compare these approaches. Throughout the study, researchers will monitor the incidence of venous thromboembolic events on days 1, 21, and 90 post-surgery. Quality of life will also be evaluated at these time points. Participants will undergo regular assessments to track safety and effectiveness over the three-month period following their surgery.