Actively Recruiting
Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers
Led by National Institute of Neurological Disorders and Stroke (NINDS) · Updated on 2026-05-05
275
Participants Needed
1
Research Sites
675 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: \- Electrical impedance myography (EIM) is a new technique being studied to see if it is helpful in evaluating muscle disorders and nerve disorders. EIM looks at how a mild, painless electrical current travels through muscles. Researchers want to gain experience in using the EIM device. They will collect information on the results of using it on people with and without nerve and muscle diseases, and compare that with information from other standard tests. First, they will test the device on healthy people. Then they will test people with a variety of neuromuscular diseases. Because the test is noninvasive and not painful, researchers will test both children and adults. Objectives: \- To gain experience using the EIM muscle testing device. Eligibility: * Healthy volunteers at least 2 years old. * Individuals at least 2 years old who have neuromuscular disease. Design: * Participants will be screened with a medical history and physical exam. * Participants will have one 2-3 hour clinic visit. Researchers may request follow-up visits. * Participants will be tested with the EIM device. The device and small electrodes will be placed on their skin. An electric current will pass through the device, but the participants will not feel this. * Participants may have an ultrasound test. A gel will be put on their skin, and a device will be moved over the skin. * Participants may have a nerve test. Electrodes will be placed on their skin, and they will feel a small shock. * Participants may have a test where a thin needle is inserted in their muscle.
CONDITIONS
Official Title
Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy adults, male or female, aged 18 years or older
- Healthy children, male or female, aged 7 to 18 years
- Adults and children aged 2 years or older with suspected or diagnosed neuromuscular disorders including motor neuron disease, myopathy, neuropathy, or movement disorders
- Ability to understand and willingness to sign written informed consent
- Willingness to comply with all study procedures and availability for study duration
You will not qualify if you...
- Adults and children with medical conditions requiring medications that affect physiological measures being tested, such as diabetes, kidney or liver disease
- History of stroke, muscle disorders, peripheral neuropathy, or spine surgery in healthy volunteers
- No clinical evidence of neuromuscular disorder on evaluation for participants with suspected neuromuscular disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
C
Candida C Silva
CONTACT
T
Tanya J Lehky, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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