Actively Recruiting
Electrical Impedance Tomography for Assessment of Pulmonary Hypertension
Led by University of Sao Paulo General Hospital · Updated on 2026-03-05
120
Participants Needed
1
Research Sites
135 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Pulmonary hypertension is a serious and progressive disease that is difficult to treat and diagnose, mainly because its symptoms are nonspecific and often delay recognition. Early diagnosis is a major challenge. Although several tests may suggest the disease, the definitive diagnosis still requires right heart catheterization, an invasive procedure that directly measures pulmonary hemodynamics such as pulmonary artery pressure, cardiac output, and vascular resistance. Electrical impedance tomography (EIT) is a non-invasive, radiation-free bedside monitoring method that can evaluate ventilation and pulmonary perfusion. The number of studies investigating perfusion with EIT has been increasing, since the possibility of having a safe, radiation-free, and repeatable method available at the bedside is of great clinical interest in different fields of medicine. Our hypothesis is that EIT provides information that correlates with the findings of right heart catheterization in patients with suspected pulmonary arterial hypertension (PAH). EIT may serve as a useful screening tool prior to catheterization and may also help in risk stratification of patients with pulmonary hypertension
CONDITIONS
Official Title
Electrical Impedance Tomography for Assessment of Pulmonary Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a diagnosis or clinical suspicion of pulmonary arterial hypertension (PAH) who have a medical indication for right heart catheterization.
- Patients evaluated at the Pulmonology Service of InCor-HCFMUSP.
You will not qualify if you...
- Pregnancy.
- Structural heart diseases such as atrial septal defect, ventricular septal defect, or valvular disease.
- Cardiac arrhythmias.
- Presence of a cardiac pacemaker or other implantable electronic device.
- Skin lesions on the chest that prevent placement of the EIT electrode belt.
- WHO functional class IV of New York Heart Association.
- Inability to perform a voluntary respiratory pause of at least 30 seconds or inability to understand and follow instructions.
- Decline to participate by not signing informed consent or refusal by the medical team.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP
São Paulo, São Paulo, Brazil, 05403-900
Actively Recruiting
Research Team
M
Marcelo BP Amato, MD PhD
CONTACT
J
Jade Lara de Melo, PT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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