Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07453017

Electrical Impedance Tomography for Assessment of Pulmonary Hypertension

Led by University of Sao Paulo General Hospital · Updated on 2026-03-05

120

Participants Needed

1

Research Sites

135 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Pulmonary hypertension is a serious and progressive disease that is difficult to treat and diagnose, mainly because its symptoms are nonspecific and often delay recognition. Early diagnosis is a major challenge. Although several tests may suggest the disease, the definitive diagnosis still requires right heart catheterization, an invasive procedure that directly measures pulmonary hemodynamics such as pulmonary artery pressure, cardiac output, and vascular resistance. Electrical impedance tomography (EIT) is a non-invasive, radiation-free bedside monitoring method that can evaluate ventilation and pulmonary perfusion. The number of studies investigating perfusion with EIT has been increasing, since the possibility of having a safe, radiation-free, and repeatable method available at the bedside is of great clinical interest in different fields of medicine. Our hypothesis is that EIT provides information that correlates with the findings of right heart catheterization in patients with suspected pulmonary arterial hypertension (PAH). EIT may serve as a useful screening tool prior to catheterization and may also help in risk stratification of patients with pulmonary hypertension

CONDITIONS

Official Title

Electrical Impedance Tomography for Assessment of Pulmonary Hypertension

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a diagnosis or clinical suspicion of pulmonary arterial hypertension (PAH) who have a medical indication for right heart catheterization.
  • Patients evaluated at the Pulmonology Service of InCor-HCFMUSP.
Not Eligible

You will not qualify if you...

  • Pregnancy.
  • Structural heart diseases such as atrial septal defect, ventricular septal defect, or valvular disease.
  • Cardiac arrhythmias.
  • Presence of a cardiac pacemaker or other implantable electronic device.
  • Skin lesions on the chest that prevent placement of the EIT electrode belt.
  • WHO functional class IV of New York Heart Association.
  • Inability to perform a voluntary respiratory pause of at least 30 seconds or inability to understand and follow instructions.
  • Decline to participate by not signing informed consent or refusal by the medical team.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP

São Paulo, São Paulo, Brazil, 05403-900

Actively Recruiting

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Research Team

M

Marcelo BP Amato, MD PhD

CONTACT

J

Jade Lara de Melo, PT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Electrical Impedance Tomography for Assessment of Pulmonary Hypertension | DecenTrialz