Developing an Electrical Impedance Tomography Prognostic Model for Acute Respiratory Distress Syndrome in Adults Aged 18 to 80

What this Trial Is About

Researchers are conducting a multicenter, prospective observational study to develop and validate a prognostic model using Electrical Impedance Tomography EIT for patients with Acute Respiratory Distress Syndrome ARDS. The study focuses on understanding the pathophysiological features of ARDS and the causes of ventilator-induced lung injury, aiming to create a model that can reveal lung injury and heterogeneity. This model will help classify patient risk and guide personalized treatment approaches. Participants with ARDS will be divided into two groups a training cohort and a validation cohort. The study does not involve any experimental treatments but observes patients under usual care to collect data related to lung function and injury through EIT. This observational approach allows researchers to analyze the progression and characteristics of lung damage without altering standard treatment. During the study, participants will be monitored for various outcomes including the 28-day mortality rate, ICU and hospital mortality rates over different time frames, duration of mechanical ventilation, ventilator-free days, and lengths of stay in ICU and hospital. These measures will help evaluate the prognostic models accuracy. The study will track patients from enrollment through 28 days and up to 24 weeks for certain outcomes, supporting long-term observation of clinical status and recovery.

Electrical Impedance Tomography-Based Prognostic Model for ARDS