Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06436950

Electrical Phrenic Nerve Stimulation in Patients With VIDD

Led by Peking University Third Hospital · Updated on 2024-11-12

40

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to examine efficacy of transcutaneous electrical phrenic nerve stimulation (TEPNS) in ventilator-induced diaphragmatic dysfunction (VIDD). The investigators recruit VIDD patients, and randomly assign the patients into TEPNS group and control group. TEPNS group receives TEPNS twice a day for consecutive 5 days. Control group only receives usual care. The investigators collect diaphragm function indicators and outcomes to evaluate the efficacy.

CONDITIONS

Official Title

Electrical Phrenic Nerve Stimulation in Patients With VIDD

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 years or older
  • Ventilated for at least 48 hours with an expected ICU stay of more than 7 days
  • Diaphragm thickening fraction less than 25%
Not Eligible

You will not qualify if you...

  • Having a pacemaker
  • Skin lesions that could interfere with electrode probes
  • Previous diaphragmatic nerve paralysis
  • Body mass index over 35 kg/m2
  • Severe chronic obstructive pulmonary disease (FEV1/FVC less than 30%)
  • Pregnancy or breastfeeding
  • Decision to withhold life-sustaining treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University Third Hospital

Beijing, Beijing Municipality, China, 100191

Actively Recruiting

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Research Team

Z

Zongyu Wang, Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Electrical Phrenic Nerve Stimulation in Patients With VIDD | DecenTrialz