Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT06265636

Electrical Stimulation of the Mandibular Nerve for Pain and Function Management in Temporomandibular Disorders

Led by OrigenKinesis fisioterapia · Updated on 2025-08-05

40

Participants Needed

1

Research Sites

167 weeks

Total Duration

On this page

Sponsors

O

OrigenKinesis fisioterapia

Lead Sponsor

U

Universidad Rey Juan Carlos

Collaborating Sponsor

AI-Summary

What this Trial Is About

Temporomandibular disorders (TMD) encompass dysfunction and pain of the masticatory muscles and temporomandibular joint (TMJ). Pain in the TMJ, restricted jaw movement, and joint sounds are common conditions in this disorder. This can impact patients' ability to perform daily activities such as eating, speaking, laughing, or yawning, significantly affecting their quality of life. The TMJ and masticatory muscles are innervated by the auriculotemporal branch and the mandibular nerve (V3), a branch of the trigeminal nerve. An estimated 60% to 70% of the population shows signs of TMD, of which up to 12% report intense symptoms requiring treatment. Percutaneous electrical nerve stimulation (PENS) could be a clinically relevant therapy in TMD patients applied through minimally invasive physiotherapy. To our knowledge, there are no trials evaluating the non-surgical clinical efficacy of PENS on the mandibular nerve. The project's objective is to assess the effectiveness of PENS on the mandibular nerve in this type of condition.

CONDITIONS

Official Title

Electrical Stimulation of the Mandibular Nerve for Pain and Function Management in Temporomandibular Disorders

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with local myofascial pain and/or increased tension in the masticatory muscles.
  • Diagnosed with myofascial pain from temporomandibular disorder (TMD) according to RDC/TMD.
  • No temporomandibular disc displacement with or without reduction.
  • Pain in masticatory muscles with limited mouth opening less than 40 mm.
  • Good general health without chronic diseases affecting the temporomandibular joint or muscles.
  • Provided written consent to participate in the study.
Not Eligible

You will not qualify if you...

  • Injury to the face or head during study participation.
  • Previous surgical procedures in the craniocervical region or degenerative neurological diseases.
  • Sudden illness preventing study participation.
  • Desire to withdraw from the study.
  • Symptoms evolving for less than 2 weeks.
  • Inability to understand instructions or sign informed consent.
  • Minor patients.
  • Regular use of muscle relaxants, anticonvulsants, antidepressants, or anxiolytics.
  • Facial paralysis.
  • Presence of dental-origin infectious or inflammatory disease.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Origenkinesis Fisioterapia

Alcorcón, Madrid, Spain, 28925

Actively Recruiting

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Research Team

H

Hector Mardomingo Medialdea, Phd

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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