Actively Recruiting
Electrical Stimulation for the Treatment of Optic Neuropathies
Led by Stanford University · Updated on 2025-07-08
40
Participants Needed
1
Research Sites
248 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The overall aim of this study is to see whether long-term electrical stimulation with a home-stimulation device works well and is safe for the treatment of open-angle glaucoma. Open-Angle Glaucoma is a disease where the nerves in the back of your eye die off faster than expected regardless of your eye pressure.
CONDITIONS
Official Title
Electrical Stimulation for the Treatment of Optic Neuropathies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant must be at least 18 years old
- Participant must be able to follow study requirements and complete all scheduled activities
- Clinical diagnosis consistent with glaucoma with mean deviation worse than -3 on Humphrey Visual Field 24-2 test
- Reliable visual field test results with fixation losses and false positives below 20%
- Eye pressure must be clinically stable as determined by the investigator
- If both eyes qualify, the worse eye or chosen eye may be included
- Participant must understand and sign informed consent, or have it read to them if vision impaired
You will not qualify if you...
- Unable to comply with study procedures or follow-up visits
- History of ocular herpes zoster
- Presence of pathological nystagmus
- Visually significant retinopathy such as diabetic retinopathy or retinitis pigmentosa
- Corneal opacification or lack of optical clarity
- Uveitis or other ocular inflammatory diseases
- Presence of electric or electronic implants like pacemakers
- Acute conjunctivitis
- Acute autoimmune disease
- Pregnant or lactating individuals
- Physical or mental conditions increasing risk or interfering with study, including dementia
- Unresected brain tumors
- Implanted intracranial magnetic metals not compatible with MRI (excluding dental implants and titanium plates)
- Any skin damage
- Children and comatose patients
- History of epileptic seizure within the last 10 years
- Uncontrolled systemic hypertension or diabetes
- Unable or unwilling to travel, comply with study, or confirm follow-up
- Participation in vision training/stimulation studies in the last 12 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Byers Eye Institute
Palo Alto, California, United States, 94303
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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