Actively Recruiting
Electro-acupuncture to Treat Disorder of Consciousness
Led by The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine · Updated on 2024-09-19
50
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
With the rapid development of life support technology, more and more people can survive severe brain injury. Some survivors regain consciousness after a period of coma, however, many patients develop prolonged disorders of consciousness (DOC), which poses a therapeutic challenge for clinicians and a heavy burden for their families. The investigators design an Electro-acupuncture to treat disorder of consciousness (AcuDoc) trial with the aim of validating the clinical effect of electroacupuncture in treating DOC and exploring its therapeutic mechanisms by integrating EEG, neuroimaging, evoked potential tests, and behavioral assessments.
CONDITIONS
Official Title
Electro-acupuncture to Treat Disorder of Consciousness
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 18 years
- Cerebral damage due to traumatic brain injury
- Diagnosed with unresponsive wakefulness syndrome (UWS) or minimally conscious state (MCS) based on at least two Coma Recovery Scale-Revised assessments
- Between 4 and 16 weeks from the onset of brain injury
- Informed consent obtained
You will not qualify if you...
- History of neurological or psychiatric disorder prior to the brain injury
- Uncontrolled seizures or status epilepticus
- Unstable vital signs requiring vasoactive agents
- Use of general anesthetics or central acting sedatives
- Lack of intact skin at acupoints or sham points
- Medical illness interfering with outcome assessments or follow-up
- Pregnant patients
- Currently participating in other investigational trials
- High likelihood of not adhering to study treatment or follow-up regimen
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Guangzhou, Guangdong, China, 510120
Actively Recruiting
Research Team
F
Fang Yuan, PhD
CONTACT
J
Jixiang Chen, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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