Actively Recruiting
Electroacupuncture Regulation of Immune Cells in Herpes Zoster
Led by First People's Hospital of Hangzhou · Updated on 2026-02-03
8
Participants Needed
1
Research Sites
163 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Herpes Zoster (HZ), caused by the Varicella-Zoster Virus (VZV), is a common infection characterized by localized pain and blistering, with higher incidence in females. HZ affects patients' physical health, mental well-being, and quality of life. The immune system is critical in HZ pathogenesis. Studies show acupuncture relieves pain, modulates immunity, and may lower postherpetic neuralgia (PHN) risk. However, evidence is limited on whether electroacupuncture (EA) alleviates HZ by modulating immune cells. Using mass cytometry (CyTOF), this study will analyze peripheral immune cell changes pre- and post-EA to explore its regulatory effects on HZ immunity. This study will recruit HZ patients and healthy controls (HC), dividing patients into medication-only and medication+EA groups to assess EA's potential immunomodulatory effects in HZ treatment.
CONDITIONS
Official Title
Electroacupuncture Regulation of Immune Cells in Herpes Zoster
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 50 to 70 years
- Diagnosed with Herpes Zoster within 7 days
- No prior antiviral, analgesic, or other treatments for the current illness
- Herpetic lesions limited to the trunk, within 1 to 3 dermatomes
- Willing to participate and has signed informed consent
- Healthy female controls matched in age without history of HZ or major diseases
- Clear consciousness and ability to communicate
- Understands the study and willing to comply
- Signed informed consent form
You will not qualify if you...
- Special types of herpes zoster such as ophthalmic, otic, visceral, meningeal, or zoster sine herpete
- Women planning to conceive, pregnant, or breastfeeding
- Severe primary diseases affecting circulatory, respiratory, endocrine systems, or systemic failure
- Bleeding tendencies
- Use of corticosteroids or immunosuppressants within the past month
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Affiliated Hangzhou First People's Hospital
Hangzhou, Zhejiang, China, 310053
Actively Recruiting
Research Team
Y
Yan Shi
CONTACT
M
Mingqi Tu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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