Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT07003763

Electroacupuncture on Treating Cancer-related Depression

Led by Shanghai Municipal Hospital of Traditional Chinese Medicine · Updated on 2025-12-23

86

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cancer-related depression (CRD) is a common psychological condition among cancer patients during diagnosis, treatment, and recovery, and is associated with reduced quality of life, impaired immune function, and poorer clinical outcomes. As cancer incidence and mortality continue to rise in China, the psychological burden on patients is receiving increasing attention. Electroacupuncture (EA) has shown potential in treating various types of depression and related somatic symptoms, but evidence regarding its efficacy, safety, and long-term effects in CRD remains limited. This randomized controlled trial aims to evaluate the short- and long-term efficacy and safety of EA for CRD, with the goal of providing evidence to support effective and optimized treatment strategies.

CONDITIONS

Official Title

Electroacupuncture on Treating Cancer-related Depression

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Presence of depression caused by cancer or cancer treatments, meeting DSM-V criteria for depressive disorder
  • Age between 18 and 75 years, any gender
  • Baseline Hamilton Depression Rating Scale-17 score greater than 17
  • Eastern Cooperative Oncology Group performance status score of 2 or less
  • No previous acupuncture treatment
  • Ability to understand study procedures and provide written informed consent
Not Eligible

You will not qualify if you...

  • Planned surgery, chemotherapy, radiotherapy, immunotherapy, or other active cancer treatments during the study
  • History of major depressive episodes before cancer diagnosis
  • Cancer-related pain with a Pain Rating Index score of 4 or higher
  • Life expectancy of 12 months or less
  • Severe ulcers, abscesses, or active skin infections near acupuncture sites
  • Serious dysfunction of major organs or other severe systemic illnesses
  • Pregnant or breastfeeding women
  • Participation in another clinical trial within the past 30 days
  • Presence of a cardiac pacemaker or implanted electronic medical devices

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai Municipal Hospital of Traditional Chinese Medicine

Shanghai, China

Actively Recruiting

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Research Team

X

Xuan Yin, Doctor

CONTACT

T

Tao Guo, Master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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