Actively Recruiting

Phase 2
Age: 18Years - 105Years
FEMALE
NCT04760327

Electrochemotherapy of Gynecological Cancers

Led by Institute of Oncology Ljubljana · Updated on 2024-10-17

30

Participants Needed

1

Research Sites

287 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To determine the effectiveness, feasibility and safety of electrochemotherapy in treatment of local and/or regional recurrences of gynecological cancers with electrochemotherapy in which standard treatment options have been exhausted.

CONDITIONS

Official Title

Electrochemotherapy of Gynecological Cancers

Who Can Participate

Age: 18Years - 105Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Local or regional relapse of gynecological tumors with exhausted standard treatment options
  • Age over 18 years
  • Life expectancy longer than 3 months
  • Karnofsky performance status 70 or higher, or WHO performance status less than 2
  • At least 2 weeks since last treatment
  • Mentally capable of understanding information about treatment and possible side effects
  • Able to give informed consent
  • Case reviewed by a multidisciplinary team before trial entry
  • Suitable for anesthesia
Not Eligible

You will not qualify if you...

  • Presence of visceral, bone, or diffuse metastases
  • Life-threatening infection, heart failure, liver failure, or other severe systemic diseases
  • Significant reduction in respiratory function
  • Age under 18 years
  • Coagulation disorders not responsive to vitamin K or fresh frozen plasma
  • Cumulative bleomycin dose of 400 mg/m2 or more
  • Impaired kidney function with creatinine over 150 µmol/l
  • History of epilepsy
  • Pregnancy
  • Unable to understand the study purpose or unwilling to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Institute of oncology Ljubljna

Ljubljana, Slovenia, 1000

Actively Recruiting

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Research Team

G

Gregor Serša, PhD

CONTACT

M

Maja Čemažar, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Electrochemotherapy of Gynecological Cancers | DecenTrialz