Actively Recruiting

Age: 1Month - 18Years
All Genders
NCT03419260

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Led by Children's Hospital of Philadelphia · Updated on 2025-02-04

2500

Participants Needed

1

Research Sites

511 weeks

Total Duration

On this page

Sponsors

C

Children's Hospital of Philadelphia

Lead Sponsor

N

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies. This is a single-center prospective observational study. The investigators aim to: (1) track critically ill patients undergoing clinically indicated EEG monitoring and seizure management to identify risk factors for electrographic seizures, (2) create prediction models guiding EEG monitoring resources to the patients at highest risk for seizures, and (3) evaluate our current management strategy in terms of safety.

CONDITIONS

Official Title

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Who Can Participate

Age: 1Month - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Care in the Children's Hospital of Philadelphia Pediatric ICU
  • Clinically indicated continuous EEG monitoring
  • Age greater than 1 month to 18 years
Not Eligible

You will not qualify if you...

  • Admission for Phase 2 (intracranial) EEG monitoring
  • Expected discontinuation of technological support within the next two days due to underlying medical or neurological problems

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

N

Nicholas S Abend, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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