Actively Recruiting
Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
Led by Children's Hospital of Philadelphia · Updated on 2025-02-04
2500
Participants Needed
1
Research Sites
511 weeks
Total Duration
On this page
Sponsors
C
Children's Hospital of Philadelphia
Lead Sponsor
N
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies. This is a single-center prospective observational study. The investigators aim to: (1) track critically ill patients undergoing clinically indicated EEG monitoring and seizure management to identify risk factors for electrographic seizures, (2) create prediction models guiding EEG monitoring resources to the patients at highest risk for seizures, and (3) evaluate our current management strategy in terms of safety.
CONDITIONS
Official Title
Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Care in the Children's Hospital of Philadelphia Pediatric ICU
- Clinically indicated continuous EEG monitoring
- Age greater than 1 month to 18 years
You will not qualify if you...
- Admission for Phase 2 (intracranial) EEG monitoring
- Expected discontinuation of technological support within the next two days due to underlying medical or neurological problems
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
N
Nicholas S Abend, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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