Actively Recruiting
Electrolysed Saline Rinse as an Adjunct for Treatment of Chronic Periodontitis
Led by University of Ljubljana · Updated on 2026-05-11
60
Participants Needed
1
Research Sites
130 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study will be conducted as a prospective, double-blind, parallel, randomized, placebo-controlled study at the Dental Clinic of University Medical Centre Ljubljana. It will involve a one-month test period, during which the test subjects will use either placebo, Electrolysed Oxidising Saline (EOS) or chlorhexidine (CHX) in the form of a mouthwash as an adjunct to the non-surgical treatment of chronic periodontitis (i.e. root planing and scaling). The study will include 60 subjects selected from consecutively scheduled patients referred by their personal dentists for periodontal treatment at the Dental Clinic of University Medical Centre Ljubljana.
CONDITIONS
Official Title
Electrolysed Saline Rinse as an Adjunct for Treatment of Chronic Periodontitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical attachment loss 25 5 mm on at least two teeth in two different jaw quadrants
- Presence of stable occlusion
- At least 16 teeth present, with at least 12 suitable for evaluation (excluding wisdom teeth, orthodontic wires, bridges, crowns, and implants)
You will not qualify if you...
- Chronic systemic diseases such as diabetes, cancer, HIV infection, metabolic bone diseases, or diseases affecting wound healing
- Undergoing radiation or chemotherapy
- Taking immunosuppressants, antiepileptic drugs, calcium antagonists, or nonsteroidal anti-inflammatory drugs
- Antibiotic treatment in the past 12 months
- Known allergy to chlorhexidine
- Previous scaling and root planing or surgical periodontal treatment in the past year
- Pregnant or breastfeeding
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University Medical Centre Ljubljana
Ljubljana, Slovenia, 1000
Actively Recruiting
Research Team
R
Rok Gašperšič, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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