Actively Recruiting

Phase 3
Age: 21Years +
All Genders
ID06702007

eHaRT-A: Adapting an Evidence-based Harm Reduction Treatment into a Virtual Telehealth Intervention for People with Lived Experience of Homelessness and Alcohol Use Disorder

Led by University of Washington · Updated on 2025-07-08

160

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

Sponsors

U

University of Washington

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the adaptation of a proven in-person harm-reduction treatment for alcohol use disorder (AUD), called HaRT-A, into a digital telehealth platform named eHaRT-A. This study focuses on individuals with lived experience of homelessness who have AUD and are living in permanent supportive Housing First (HF) facilities. The aim is to determine if eHaRT-A can better reduce alcohol-related harm and improve quality of life compared to the usual supportive services offered by HF programs. The study includes two phases: Phase 1 involves co-developing and testing the eHaRT-A telehealth platform with input from HF residents, staff, and management to ensure it is usable, feasible, and acceptable. Phase 2 is a randomized controlled trial comparing the eHaRT-A intervention delivered via one-on-one video sessions against standard HF services. eHaRT-A maintains the core components of HaRT-A, which include tracking alcohol-related harm, setting personalized harm-reduction and health goals, and discussing safer drinking strategies. Participants will be adults registered at HF sites who meet criteria for current AUD and are actively drinking. The study involves assessments at baseline, during treatment, and at 1- and 3-month follow-ups. These include self-report questionnaires on alcohol use, health-related quality of life, and urine tests for alcohol biomarkers. Qualitative interviews will also gather feedback on the intervention's acceptability and effectiveness. The study will monitor changes in alcohol use, alcohol-related harm, and quality of life over time while assessing the feasibility of delivering eHaRT-A within HF settings.

CONDITIONS

Brief Title

Electronic Harm Reduction Treatment for Alcohol

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Being at least 21 years of age
  • Speak English fluently
  • Currently a registered client at one of the Housing First sites
  • Currently drinking (used alcohol in the past 2 weeks)
  • Meeting criteria for current alcohol use disorder according to DSM-5 (score >= 2 on SCID-5-CV)
Not Eligible

You will not qualify if you...

  • Enrollment in any related treatment studies (including studies by this research team)
  • Refusal or inability to consent
  • Constituting a risk to the safety and security of residents or staff

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 3 weeks

Participants receive harm reduction treatment for alcohol use through one-on-one video sessions using the eHaRT-A telehealth platform or continue with Housing First supportive services as usual.

Visits at baseline, week 2, and week 3

Follow-up

Duration - 3 months

Participants complete follow-up assessments on alcohol use, quality of life, and provide feedback on the intervention to evaluate its effectiveness and acceptability.

1- and 3-month follow-up visits

Trial Site Locations

Total: 1 location

1

Downtown Emergency Service Center

Seattle, Washington, United States, 98104

Actively Recruiting

Loading map...

Research Team

E

Emily Taylor

T

Tessa Frohe, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Similar Trials

A Combined Neurofeedback-TMS Intervention for Alcohol Use Di...

Alcohol Use Disorder

Actively Recruiting

1 location

A Phase I/II Study of CMND-100 Tolerability, Safety, and Pha...

Alcohol Use Disorder

Actively Recruiting

4 locations

Non-inferiority Trial Comparing Electronic and Face-to-face ...

Alcohol Use Disorder

Actively Recruiting

2 locations

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

Combining behavioral harm-reduction treatment and extended-release naltrexone for people experiencing homelessness and alcohol use disorder in the USA: a randomised clinical trial.

Susan E Collins, Mark H Duncan, Andrew J Saxon...

https://pubmed.ncbi.nlm.nih.gov/33713622

Project-based Housing First for chronically homeless individuals with alcohol problems: within-subjects analyses of 2-year alcohol trajectories.

Susan E Collins, Daniel K Malone, Seema L Clifasefi...

https://pubmed.ncbi.nlm.nih.gov/22390516

Randomized controlled trial of harm reduction treatment for alcohol (HaRT-A) for people experiencing homelessness and alcohol use disorder.

Susan E Collins, Seema L Clifasefi, Lonnie A Nelson...

https://pubmed.ncbi.nlm.nih.gov/30851620