Actively Recruiting
ElectroPhySiological Characterization Of the Arrhythmia Substrate for Sudden Cardiac Death PrEdiction
Led by University Hospital, Bordeaux · Updated on 2025-07-10
210
Participants Needed
3
Research Sites
378 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
EP-SCOPE is a prospective, multicentric, non-randomized pilot study that aims to estimate the risk of life-threatening ventricular arrhythmia through use of advanced electrophysiological studies in patients with ischemic or non-ischemic cardiomyopathy with left ventricular ejection fraction (LVEF) \<50% and risk factors of ventricular arrhythmia, otherwise not considered for implantation of an implantable cardioverter defibrillator (ICD). The objective is to assess the effectiveness of a risk stratification strategy based on detailed electrophysiological exploration of the left ventricle and programmed ventricular stimulation.
CONDITIONS
Official Title
ElectroPhySiological Characterization Of the Arrhythmia Substrate for Sudden Cardiac Death PrEdiction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with cardiomyopathy with 35%<LVEF<50% and at least one risk factor
- Patients with cardiomyopathy with LVEF�35% and an indication for cardiac resynchronisation
You will not qualify if you...
- Patients who are minors or aged 80 or over
- Patients with unstable coronary artery disease
- Myocardial infarction less than 40 days old
- Coronary revascularisation <90 days
- Patients with intracardiac thrombus
- Patients with a mechanical heart valve
- Patient implanted with an automatic defibrillator
- Patient life expectancy <1 year
- Pregnant or breast-feeding women
- Anti-arrhythmic drugs other than beta-blockers and amiodarone
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
CHU de Clermont-Ferrand
Clermont-Ferrand, France, 63000
Actively Recruiting
2
CHU de Bordeaux - Hôpital Cardiologique du Haut-Lévêque
Pessac, France, 33604
Actively Recruiting
3
CHU de Saint-Etienne
Saint-Etienne, France, 42270
Actively Recruiting
Research Team
S
Sylvain PLOUX, MD
CONTACT
M
Mélissa LABEQUE
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here